Club-record signing Aubameyang shone on his Gunners debut last weekend, scoring in a 5-1 victory over Everton.
The Gabon international has taken the number 14 shirt at Arsenal previously worn by Henry – the club’s all-time leading goalscorer – but Wenger says it is too early for comparisons.
“It’s a bit too early to compare him to the best player ever who played here,’ Wenger said.
“He has played one game. But it’s a good example to follow.
“It is an ambitious statement but it is a good one.
“The best goalscorer ever in Arsenal’s history. It doesn’t mean he will score as many goals, but why not?”
Uwe Rosler was sacked by Fleetwood following a 3-0 reverse at Doncaster which condemned Town to a seventh straight defeat in all competitions.
Cambridge interim head coach Joe Dunne was pleased with how his side adapted to beat Grimsby 3-1.
Southend manager Chris Powell led the applause for Jason Demetriou after the right-back scored twice in the 3-1 win against Portsmouth at Roots Hall.
Morecambe boss Jim Bentley was the happier manager after Gregg Wylde's 90th-minute strike earned his side a point in their 1-1 draw with Forest Green.
Manager Gareth Ainsworth described Wycombe's 2-0 win at Cheltenham as a thoroughly professional performance.
Skipper Richard Wood scored the winner just before half time as in-form Rotherham pulled off a 1-0 victory at League One leaders Shrewsbury.